Nootropic and anxiolytic peptides such as Selank and Semax are studied for cognition, focus, stress resilience and neuroprotection, acting on neurotransmitter and BDNF pathways. We review the mechanisms and the (often Russian-origin) evidence base behind them.
Profiles
- DSIP: Mechanism, Benefits & Research Evidence
- Selank: Mechanism, Benefits & Research Evidence
- Semax: Mechanism, Benefits & Research Evidence
Comparisons
Questions & Evidence
- How does Semax cross the BBB despite being a heptapeptide, and what does its actual brain pharmacokinetic curve look like when delivered intranasally vs. subcutaneously?
- Is Semax's nootropic reputation in the West a translation artifact — Russian clinical practice uses it almost exclusively for stroke recovery, not cognitive enhancement in healthy adults?